Learn More
HINT1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A305363A

Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Bovine, Rabbit and Orangutan
Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5′-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.Specifications
HINT1 | |
Polyclonal | |
Unconjugated | |
HINT1 | |
FLJ30414, FLJ32340, HINT, PKCI-1, PRKCNH1, adenosine 5′-monophosphoramidase; histidine triad nucleotide-binding protein 1; protein kinase C inhibitor 1; protein kinase C-interacting protein 1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
3094 | |
4° C | |
Liquid |
Immunoprecipitation | |
1 mg/ml | |
phosphate, tris citrate with 0.09% sodium azide; pH 7-8 | |
P49773 | |
HINT1 | |
Between 1 and 50 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.