Invitrogen™ HIP1 Monoclonal Antibody (1B11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA116748

Catalog No. AMPA6748

Description

This antibody does not react with rat samples. Suggested positive control: Hela whole cell extract, HeLa whole cell lysate.

Huntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.

Specifications

• Antigen: HIP1
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.1% sodium azide
• Gene Accession No.: O00291, Q8VD75
• Gene Symbols: HIP1
• Immunogen: Human HIP1 (~65 kDa).
• Regulatory Status: RUO
• Gene ID (Entrez): 215114, 3092
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Clone: 1B11
• Conjugate: Unconjugated
• Gene: HIP1
• Gene Alias: 2610109B09Rik; A930014B11Rik; E130315I21Rik; HIP I; hip1; HIP-1; HIP-I; huntingtin interacting protein 1; huntingtin-interacting protein 1; Huntingtin-interacting protein I; ILWEQ; Kiaa4113; mKIAA4113; SHON; SHONbeta; SHONgamma
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Bacteria
• Product Type: Antibody
• Isotype: IgG1 κ