Invitrogen™ HIP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA546708

Catalog No. PIPA546708

Description

Peptide sequence: SQQNLFDNKF DDIFGSSFSS DPFNFNSQNG VNKDEKDHLI ERLYREISGL.

Huntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.

Specifications

• Antigen: HIP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HIP1
• Gene Alias: 2610109B09Rik; A930014B11Rik; E130315I21Rik; HIP I; hip1; HIP-1; HIP-I; huntingtin interacting protein 1; huntingtin-interacting protein 1; Huntingtin-interacting protein I; ILWEQ; Kiaa4113; mKIAA4113; SHON; SHONbeta; SHONgamma
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3092
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: O00291
• Gene Symbols: HIP1
• Immunogen: Synthetic peptide directed towards the N-terminal of human HIP1 (aa 338-387).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG