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Invitrogen™ HIP1 Polyclonal Antibody
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Catalog No. PIPA593288
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100 μL
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PIPA593288 100 μL
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Catalog No. PIPA593288 Supplier Invitrogen™ Supplier No. PA593288
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SELEADLAEQ QHLRQQAADD CEFLRAELDE LRRQREDTEK AQRSLSEIER KAQANEQRYS KLKEKYSELV QNHADLLRKN AEVTKQVSMA RQAQVDLERE KKELEDSLER ISDQGQRKTQ EQLEVLESLK QELATSQREL QVLQGSLETS AQSEANWAAE FAELEKERDS LVSGAAHREE ELSALRKELQ DTQLKLASTE ESMCQLAKDQ RKMLLVGSRK AAEQVIQDAL NQLEEPPLIS CAGSADHLLS TVTSISSCIE QLEKSWSQYL ACPEDISGLL H; Positive Samples: A-549, BT-474, SW480, 293T, Mouse brain; Cellular Location: Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Nucleus, clathrin-coated vesicle membrane.

Huntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HIP1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene HIP1
Gene Accession No. O00291, Q8VD75
Gene Alias 2610109B09Rik; A930014B11Rik; E130315I21Rik; HIP I; hip1; HIP-1; HIP-I; huntingtin interacting protein 1; huntingtin-interacting protein 1; Huntingtin-interacting protein I; ILWEQ; Kiaa4113; mKIAA4113; SHON; SHONbeta; SHONgamma
Gene Symbols HIP1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 410-690 of human HIP1 (NP_0053293).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 215114, 3092
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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