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HIP1R/HIP12 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501568724
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50-156-8724 100 μL
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Catalog No. 50-156-8724 Supplier Bethyl Laboratories, Inc Supplier No. A304805A
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Huntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.

Specifications

Antigen HIP1R/HIP12
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene HIP1R
Gene Accession No. O75146
Gene Alias HIP12, HIP3, ILWEQ, HIP-12, HIP1-related protein, huntingtin interacting protein 12, huntingtin-interacting protein 1-related protein, huntingtin-interacting protein 12
Gene Symbols HIP1R
Host Species Rabbit
Immunogen Between 300 and 350
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9026
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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