Invitrogen™ HIP1R Monoclonal Antibody (1E1)

Catalog No.	Quantity
AMPA6750	100 μL

Catalog No. AMPA6750 Supplier Invitrogen™ Supplier No. MA116750

Description

Mouse Monoclonal Antibody

Suggested positive control: HeLa whole cell lysate and rat brain homogenate, Hela whole cell lysate, antigen standard for IFT57 (transient overexpression lysate), rat brain protein.

Huntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.

Specifications

• Antigen: HIP1R
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 1E1
• Concentration: Conc. Not Determined
• Conjugate: Unconjugated
• Formulation: Ascites with 0.1% sodium azide
• Gene: HIP1R
• Gene Accession No.: O75146, Q9JKY5
• Gene Alias: AA410023; HIP12; HIP-12; Hip1r; HIP1-related protein; HIP3; huntingtin interacting protein 1 related; huntingtin interacting protein 12; Huntingtin-interacting protein 12; huntingtin-interacting protein 1-related protein; ILWEQ; KIAA0655; mKIAA0655
• Gene Symbols: HIP1R
• Host Species: Mouse
• Immunogen: Human HIP1 Related-TALIN Homology Region (57 kDa).
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 29816, 81917, 9026
• Target Species: Human, Mouse, Rat, Bacteria
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1 κ