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Invitrogen™ HIP1R Polyclonal Antibody
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Catalog No. PIPA558261
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100 μL
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PIPA558261 100 μL
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Catalog No. PIPA558261 Supplier Invitrogen™ Supplier No. PA558261
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RESQEQGLRQ RLLDEQFAVL RGAAAEAAGI LQDAVSKLDD PLHLRCTSSP DYLVSRAQEA LDAVSTLEEG HAQYLTSLAD ASALVAALTR FSHLAADTII NGGATSHLA Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 87%.

Huntingtin disease, a neurodegenerate disease, is caused by the expansion of a polymorphic glutamine tract in huntingtin. The Huntingtin Interacting Protein 1 (HIP-1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin disease. As well as playing a role in Huntingtin disease, it is likely to be involved in the recruitment of clathrin coats to lipid membranes and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HIP1R
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene HIP1R
Gene Accession No. O75146
Gene Alias AA410023; HIP12; HIP-12; Hip1r; HIP1-related protein; HIP3; huntingtin interacting protein 1 related; huntingtin interacting protein 12; Huntingtin-interacting protein 12; huntingtin-interacting protein 1-related protein; ILWEQ; KIAA0655; mKIAA0655
Gene Symbols HIP1R
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human HIP1R. Recombinant protein control fragment (Product #RP-102811).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9026
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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