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Invitrogen™ HIPPI Polyclonal Antibody
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Catalog No. PIPA5106283
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100 μL
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PIPA5106283 100 μL
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Catalog No. PIPA5106283 Supplier Invitrogen™ Supplier No. PA5106283
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total IFT57.

HIPPI is required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HIPPI
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene IFT57
Gene Accession No. Q8BXG3, Q9NWB7
Gene Alias 4833420A15Rik; dermal papilla-derived protein 8; DERP8; Esrrbl1; estrogen-related receptor beta like 1; estrogen-related receptor beta-like protein 1; FLJ10147; HIP1 protein interactor; HIP1-interacting protein; Hippi; huntingtin interacting protein-1 interacting protein; huntingtin-interacting protein-1 protein interactor; IFT57; intraflagellar transport 57; intraflagellar transport 57 homolog; intraflagellar transport protein 57 homolog; MHS4R2; Vestrogen-related receptor beta like 1
Gene Symbols IFT57
Host Species Rabbit
Immunogen A synthesized peptide derived from human IFT57(Accession Q9NWB7), corresponding to amino acid residues F84-S134.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 303968, 478553, 55081, 73916
Target Species Human, Mouse, Rat, Canine
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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