Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. HIRA Monoclonal Antibody (WC119.2H11), Active Motif™ 

HIRA Monoclonal Antibody (WC119.2H11), Active Motif™
SDP

Catalog No. 501992720
Encompass
Change view
Click to view available options
Quantity:
10 μg
100 μg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
50-199-2720 10 μg
50-199-2719 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
Catalog No. 50-199-2720 Supplier Active Motif Supplier No. 39558
Only null left
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochromatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.

Specifications

Antigen HIRA
Applications Western Blot
Classification Monoclonal
Clone WC119.2H11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene HIRA
Gene Accession No. P54198, Q61666
Gene Alias AA138857; D16Ertd95e; DGCR1; DiGeorge critical region gene 1; Gm15797; HIR; HIR histone cell cycle regulation defective homolog A; Hira; histone cell cycle regulation defective homolog A; histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulator; N28177; OTTMUSG00000026264; Protein HIRA; TUP1; TUP1-like enhancer of split gene 1; TUP1-like enhancer of split protein 1; Tuple1
Gene Symbols HIRA
Host Species Mouse
Immunogen This HIRA antibody was raised against a GST-fusion protein containing residues 421-729 of human HIRA.
Purification Method Protein G
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15260, 7290
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.