HIRA Rabbit anti-Human, Mouse, Polyclonal, liquid, OriGene

Rabbit Polyclonal Antibody

Supplier:  OriGene TA890126

Catalog No. 50-168-4811

Description

HIRA is a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this protein in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. It plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate protein in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development.

Specifications

• Antigen: HIRA
• Classification: Polyclonal
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P54198, Q61666
• Gene Symbols: HIRA
• Immunogen: Recombit protein of human HIRA
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: HIRA
• Gene Alias: DGCR1, TUP1, TUPLE1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 15260, 7290
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid