Invitrogen™ HIST1H2BB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5117474

Catalog No. PIPA5117474

Description

This antibody has been tested in direct-ELISA.

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Specifications

• Antigen: HIST1H2BB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H2BC3
• Gene Alias: H2B histone family, member F; H2B.1; H2B/f; h2B-143; H2B-clustered histone 3; H2BFF; HIST1H2BB; histone 1, H2bb; histone cluster 1, H2bb; histone H2B type 1-B; Histone H2B.1; histone H2B.f
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3018, 319178
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ChIP Assay, Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: P33778, Q64475
• Gene Symbols: H2BC3, HIST1H2BB
• Immunogen: Peptide sequence around site of Lys (16) derived from Human Histone H2B type 1-B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov