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Invitrogen™ HIST1H2BH Polyclonal Antibody
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Catalog No. PIPA575322
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100 μL
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Catalog No. Quantity
PIPA575322 100 μL
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Catalog No. PIPA575322 Supplier Invitrogen™ Supplier No. PA575322
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

In eukaryotes, DNA is wrapped around histone octamers to form the basic unit of chromatin structure. The octamer is composed of histones H2A, H2B H3 and H4 and it associates with approximately 200 base pairs of DNA to form the nucleosome. The association of DNA with histones results in dense packing of chromatin, which restricts proteins involved in gene transcription from binding to DNA. Histone H1 is required for the condensation of nucleosome chains into higher order structures. Phosporylation of Histone H1 is thought be involved in this process, although the exact nature of this role has yet to be elucidated. Evidence suggests that Histone H1 is a part of a general repressor mechanism for stable repression of transcription, but it can also activate transcription of specific genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HIST1H2BH
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene H2BC9
Gene Accession No. Q64478, Q93079
Gene Alias H2B histone family, member J; H2B.j; H2B/j; h2B-221; H2BFJ; Hist1h2bh; histone 1, H2bh; histone cluster 1, H2bh; histone H2B type 1-H; Histone H2B.j; Histone H2Bj
Gene Symbols H2BC9
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the N-terminal of Human HIST1H2BH.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 319182, 8345
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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