Invitrogen™ HIST2H2AB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559477

Catalog No. PIPA559477

Description

Immunogen sequence: AVRNDEELNK LLGGVTIAQG GVLPNI Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Specifications

• Antigen: HIST2H2AB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HIST2H2AB
• Gene Alias: H2AB; HIST2H2AB; histone 2, H2ab; histone cluster 2, H2ab; histone H2A type 2-B
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 317772
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8IUE6
• Gene Symbols: HIST2H2AB
• Immunogen: Recombinant protein corresponding to Human HIST2H2AB.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG