Invitrogen™ HIST2H2BE Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596011

Catalog No. PIPA596011

Description

Positive Samples: SW480, BT-474; Cellular Location: Chromosome, Nucleus Immunogen sequence: MPEPAKSAPA PKKGSKKAVT KAQKKDGKKR KRSRKESYSI YVYKVLKQVH PDTGISSKAM GIMNSFVNDI FERIAGEASR LAHYNKRSTI TSREIQTAVR.

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Specifications

• Antigen: HIST2H2BE
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H2BC21
• Gene Alias: AV127319; GL105; H2B; H2b 613; H2B histone family, member Q; H2B.1; H2B/q; H2b-613; H2BFQ; H2BGL105; H2BQ; Hist2h2be; HIST2H2BF; histone 2, H2be; histone cluster 2, H2be; histone cluster 2, H2bf; histone H2B type 2-E; Histone H2B type 2-F; Histone H2B.q; histone H2B-GL105; Histone H2Bq; RGD1562346; T25626
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 319190, 8349
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.94 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q16778, Q64524
• Gene Symbols: H2BC21
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Histone H2B (NP_0035191).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov