Invitrogen™ HIST2H2BF Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544511

Catalog No. PIPA544511

Description

Peptide sequence: MPDPAKSAPA PKKGSKKAVT KVQKKDGKKR KRSRKESYSV YVYKVLKQVH Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

HIST2H2BF is the core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Specifications

• Antigen: HIST2H2BF
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H2BC18
• Gene Alias: HIST2H2BF; histone cluster 2, H2bf; histone H2B type 2-F; MGC131639
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 440689
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ChIP Assay, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q5QNW6
• Gene Symbols: H2BC18
• Immunogen: Synthetic peptide directed towards the N-terminal of human HIST2H2BF (aa 1-50).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov