Invitrogen™ Histone H1.1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5139832

Catalog No. PIPA5139832

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: PAKAAAASKK KPAGPSVSEL IVQAASSSKE RG.

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Histone H1.1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H1-1
• Gene Alias: H1 histone family, member 1; H1.1; H1-1; H1A; H1F1; HIST1; HIST1H1A; histone 1, H1a; histone cluster 1, H1a; histone H1.1; Histone H1a
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3024
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q02539
• Gene Symbols: H1-1
• Immunogen: Recombinant protein corresponding to Human H1-1. Recombinant protein control fragment (Product #RP-108931).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG