Invitrogen™ Histone H1.2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA542819

Catalog No. PIPA542819

Description

Peptide sequence: ASGSFKLNKK AASGEAKPKV KKAGGTKPKK PVGAAKKPKK AAGGATPKKS Sequence homology: Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 85%; Rat: 86%.

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Histone H1.2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H1-2
• Gene Alias: 0610008C09Rik; CTL-1; H1 histone family, member 2; H1 VAR.1; H1.2; H1.2 linker histone, cluster member; H1-2; H1C; H1f2; H1s-1; H1var1; His1a; Hist1h1c; histone 1, H1c; histone cluster 1, H1c; histone H1; histone H1.1; histone H1.2; Histone H1c; histone H1d; Histone H1s-1; LOC684681; MGC3992; similar to Histone H1.2 (H1 VAR.1) (H1c)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3006
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ChIP Assay, Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P16403
• Gene Symbols: H1-2, HIST1H1C
• Immunogen: Synthetic peptide directed towards the middle region of human HIST1H1C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov