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Invitrogen™ Histone H1.2 Recombinant Rabbit Monoclonal Antibody (JU43-48)
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Catalog No. PIMA532812
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PIMA532812 100 μL
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Catalog No. PIMA532812 Supplier Invitrogen™ Supplier No. MA532812
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Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Histone H1.2
Applications ChIP Assay, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JU43-48
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene H1-2
Gene Accession No. P15864, P16403
Gene Alias 0610008C09Rik; CTL-1; H1 histone family, member 2; H1 VAR.1; H1.2; H1.2 linker histone, cluster member; H1-2; H1C; H1f2; H1s-1; H1var1; His1a; Hist1h1c; histone 1, H1c; histone cluster 1, H1c; histone H1; histone H1.1; histone H1.2; Histone H1c; histone H1d; Histone H1s-1; LOC684681; MGC3992; similar to Histone H1.2 (H1 VAR.1) (H1c)
Gene Symbols H1-2, HIST1H1C
Host Species Rabbit
Immunogen Synthetic peptide within Human Histone H12 aa 1-50.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116883558, 3006, 50708
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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