Invitrogen™ Histone H1.4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544881

Catalog No. PIPA544881

Description

Peptide sequence: MSETAPAAPA APAPAEKTPV KKKARKSAGA AKRKASGPPV SELITKAVAA Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%.

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Histone H1.4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H1-4
• Gene Alias: dJ221C16.5; H1 histone family, member 4; H1 VAR.2; H1.12 linker histone, cluster member; H1.4; H1-12; H14; H1-4; H1d; H1e; H1f4; H1s-4; H1var2; Hist1h1c; Hist1h1d; Hist1h1e; histone 1, H1e; Histone 1d; Histone cluster 1; histone cluster 1, H1d; histone cluster 1, H1e; histone H1.2; histone H1.4; Histone H1b; histone H1e; histone H1s-4; MGC116819
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3008
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P10412
• Gene Symbols: H1-4, HIST1H1E
• Immunogen: Synthetic peptide directed towards the N-terminal of human HIST1H1E (aa 1-50).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG