Invitrogen™ Histone H1.4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531908

Catalog No. PIPA531908

Description

Recommended positive controls: HeLa Nucleus. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Histone H1.4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H1-4
• Gene Alias: dJ221C16.5; H1 histone family, member 4; H1 VAR.2; H1.12 linker histone, cluster member; H1.4; H1-12; H14; H1-4; H1d; H1e; H1f4; H1s-4; H1var2; Hist1h1c; Hist1h1d; Hist1h1e; histone 1, H1e; Histone 1d; Histone cluster 1; histone cluster 1, H1d; histone cluster 1, H1e; histone H1.2; histone H1.4; Histone H1b; histone H1e; histone H1s-4; MGC116819
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3008
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P10412
• Gene Symbols: H1-4, HIST1H1E
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1 and 69 of Human Histone H1.4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG