Invitrogen™ Histone H1T Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA566793

Catalog No. PIPA566793

Description

Immunogen sequence: RATTPKTVRSG RKAKGAKGKQ QQKSPVKARA SKSKLTQHHE VNVRKATSKK Highest antigen sequence identity to the following orthologs - mouse 48%, rat 48%.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.

Specifications

• Antigen: Histone H1T
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H1-6
• Gene Alias: dJ221C16.2; H1 histone family, member T (testis-specific); H1.6; H1ft; H1T; HIST1H1T; histone 1, H1t; histone cluster 1, H1t; histone H1t; Testicular H1 histone
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3010
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P22492
• Gene Symbols: H1-6
• Immunogen: Recombinant Human Histone H1T. Recombinant protein control fragment (Product #RP-107450).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov