Invitrogen™ Histone H1T Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120647

Catalog No. PIPA5120647

Description

Positive test controls include: Mouse testis, Rat testis. Immunogen sequence: NKRAKKPRAT TPKTVRSGRK AKGAKGKQQQ KSPVKARASK SKLTQHHEVN VRKATSKK.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.

Specifications

• Antigen: Histone H1T
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H1-6
• Gene Alias: dJ221C16.2; H1 histone family, member T (testis-specific); H1.6; H1ft; H1T; HIST1H1T; histone 1, H1t; histone cluster 1, H1t; histone H1t; Testicular H1 histone
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 107970, 3010
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.2 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P22492, Q07133
• Gene Symbols: H1-6
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-207 of human Histone H1t (NP_005314.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG