Invitrogen™ Histone H2A.Z Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588544

Catalog No. PIPA588544

Description

Immunogen sequence: MAGGKAGKDS GKAKTKAVSR SQRAGLQFPV GRIHRHLKSR TTSHGRVGAT AAVYSAAILE YLTAEVLELA GNASKDLKVK RITPRHLQLA IRGDEELDSL IKATIAGGGV IPHIHKSLIG KKGQQKTV; Positive Samples: HL-60, MCF-7, 22Rv1, PC-12, HepG2, Mouse testis, Mouse thymus; Cellular Location: Chromosome, Nucleus.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Specifications

• Antigen: Histone H2A.Z
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H2AZ1
• Gene Alias: 11ac; C530002L11Rik; H2A histone family member V; H2A histone family member Z; H2A histone family member Z L homeolog; H2A histone family, member V; H2A histone family, member Va; H2A histone family, member Z; H2A.F/Z; H2A.z; H2A.Z variant histone 1; H2A.Z variant histone 2; H2A.Z variant histone 2a; H2A.Z1; H2a.z-1; H2A.Z-2; H2A.ZK5; H2A.ZK5ac; H2A.Zl; h2a.zl1; h2a.zl2; H2A/z; H2AF; H2AFV; h2afva; h2afz; h2afz.L; H2AFZac; H2AV; H2az; H2AZ histone; H2AZ1; H2AZ2; h2az2a; h2aza; H2AZK11ac; H2AZK7ac; histone (H2A.Z); histone H2A.F/Z; Histone H2A.V; Histone H2A.Z; histone H2A.Zl2; histone H2A.Z-like; histone variant H2A.F/Z; hypothetical protein; purine-rich binding element protein B; RCJMB04_2h11; Unknown (protein for MGC:133654); unnamed protein product; XELAEV_18005732mg; XH2AZ
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3015, 51788, 58940, 77605, 94239
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.96 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P0C0S5, P0C0S6, P0C0S7, Q3THW5, Q71UI9
• Gene Symbols: H2AFZ, H2AZ1, H2az2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human H2AFZ (NP_0020971).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG