Invitrogen™ Histone H2A.Z Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521923

Catalog No. PIPA521923

Description

Recommended positive controls: Molt-4, Raji. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Dog (100%), Pig (100%), Chicken (100%), Sheep (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

Specifications

• Antigen: Histone H2A.Z
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H2AZ1
• Gene Alias: 11ac; C530002L11Rik; H2A histone family member V; H2A histone family member Z; H2A histone family member Z L homeolog; H2A histone family, member V; H2A histone family, member Va; H2A histone family, member Z; H2A.F/Z; H2A.z; H2A.Z variant histone 1; H2A.Z variant histone 2; H2A.Z variant histone 2a; H2A.Z1; H2a.z-1; H2A.Z-2; H2A.ZK5; H2A.ZK5ac; H2A.Zl; h2a.zl1; h2a.zl2; H2A/z; H2AF; H2AFV; h2afva; h2afz; h2afz.L; H2AFZac; H2AV; H2az; H2AZ histone; H2AZ1; H2AZ2; h2az2a; h2aza; H2AZK11ac; H2AZK7ac; histone (H2A.Z); histone H2A.F/Z; Histone H2A.V; Histone H2A.Z; histone H2A.Zl2; histone H2A.Z-like; histone variant H2A.F/Z; hypothetical protein; purine-rich binding element protein B; RCJMB04_2h11; Unknown (protein for MGC:133654); unnamed protein product; XELAEV_18005732mg; XH2AZ
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3015, 51788, 77605, 94239
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P0C0S5, P0C0S6, Q3THW5, Q71UI9
• Gene Symbols: H2AFZ, H2AZ1, H2az2
• Immunogen: Synthetic peptide corresponding to a region within amino acids 65 and 128 of Histone H2AZ.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG