Histone H2AX Rabbit, Clone: RM214, Abnova™
Rabbit monoclonal antibody raised against synthetic peptide of human Histone H2AX.
Manufacturer: Abnova Corporation MAB12802
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq]
|Rabbit monoclonal antibody raised against synthetic peptide of human Histone H2AX.|
|In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody reacts to Histone H2AX protein, independent of post-translational modifications. No cross reactivity with other histone proteins. .|
|ELISA, Immunocytochemistry, Western Blot|
|ELISA (0.2 ug/mL-1 ug/mL) Immunocytochemistry (1 ug/mL-2 ug/mL) Western Blot (0.5 ug/mL-2 ug/mL) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to C-terminus region of Histone H2AX.|
|Protein A purification|
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