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Histone H2AX Rabbit, Clone: RM214, Abnova™

Catalog No. 89934248 Shop All Abnova Corporation Products
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100 μg
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89-934-248 100 μg
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Catalog No. 89-934-248 Supplier Abnova Corporation Supplier No. MAB12802
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Description

Rabbit monoclonal antibody raised against synthetic peptide of human Histone H2AX.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq]

Specifications

Antigen Histone H2AX
Applications ELISA, Immunocytochemistry, Western Blot
Classification Monoclonal
Clone RM214
Conjugate Unconjugated
Description Rabbit monoclonal antibody raised against synthetic peptide of human Histone H2AX.
Dilution ELISA (0.2 ug/mL-1 ug/mL) Immunocytochemistry (1 ug/mL-2 ug/mL) Western Blot (0.5 ug/mL-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Gene Alias H2A.X/H2A/X/H2AX
Gene Symbols H2AFX
Host Species Rabbit
Immunogen A synthetic peptide corresponding to C-terminus region of Histone H2AX.
Purification Method Protein A purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3014
Test Specificity This antibody reacts to Histone H2AX protein, independent of post-translational modifications. No cross reactivity with other histone proteins. .
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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