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Histone H2AX Rabbit, Clone: RM214, Abnova™

Rabbit monoclonal antibody raised against synthetic peptide of human Histone H2AX.

Manufacturer:  Abnova Corporation MAB12802

Catalog No. 89-934-248


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Description

Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq]

Specifications

Specifications

Histone H2AX
RM214
Rabbit monoclonal antibody raised against synthetic peptide of human Histone H2AX.
In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
H2A.X/H2A/X/H2AX
Rabbit
IgG
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
This antibody reacts to Histone H2AX protein, independent of post-translational modifications. No cross reactivity with other histone proteins. .
ELISA, Immunocytochemistry, Western Blot
Unconjugated
ELISA (0.2 ug/mL-1 ug/mL) Immunocytochemistry (1 ug/mL-2 ug/mL) Western Blot (0.5 ug/mL-2 ug/mL) The optimal working dilution should be determined by the end user.
Liquid
H2AFX
A synthetic peptide corresponding to C-terminus region of Histone H2AX.
Protein A purification
RUO
Primary
3014
Human
SDS
Documents
Product Certifications
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