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Invitrogen™ Histone H2B Polyclonal Antibody
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Catalog No. PIPA5143705
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PIPA5143705 100 μL
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Catalog No. PIPA5143705 Supplier Invitrogen™ Supplier No. PA5143705
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Description

Rabbit Polyclonal Antibody

The antibody detects a 15 kDa* protein corresponding to the molecular mass of Histone H2B on SDS-PAGE immunoblots of human A431, Jurkat, HeLa, mouse C2C12, rat PC12, and A7r5 cells. The antibody also shows nuclear labeling in immunocytochemistry of methanol/acetone fixed cells.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Histone H2B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene H2BW2
Gene Accession No. A0A2R8Y619, O60814, P06899, P0C1H6, P10854, P23527, P33778, P57053, P58876, P62807, P70696, Q00729, Q16778, Q5QNW6, Q64475, Q64478, Q64524, Q6ZWY9, Q7Z2G1, Q8CGP1, Q8N257, Q93079, Q96A08, Q99877, Q99879, Q99880
Gene Alias 2610022J01Rik; Acetyl-Histone H2; AV127319; bA317E16.3; CG17949; CG17949-PA; CG33868; CG33868-PA; CG33870; CG33870-PA; CG33872; CG33872-PA; CG33874; CG33874-PA; CG33876; CG33876-PA; CG33878; CG33878-PA; CG33880; CG33880-PA; CG33882; CG33882-PA; CG33884; CG33884-PA; CG33886; CG33886-PA; CG33888; CG33888-PA; CG33890; CG33890-PA; CG33892; CG33892-PA; CG33894; CG33894-PA; CG33896; CG33896-PA; CG33898; CG33898-PA; CG33900; CG33900-PA; CG33902; CG33902-PA; CG33904; CG33904-PA; CG33906; CG33906-PA; CG33908; CG33908-PA; CG33910; CG33910-PA; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; Dmel\CG17949; Dmel\CG33868; Dmel\CG33870; Dmel\CG33872; Dmel\CG33874; Dmel\CG33876; Dmel\CG33878; Dmel\CG33880; Dmel\CG33882; Dmel\CG33884; Dmel\CG33886; Dmel\CG33888; Dmel\CG33890; Dmel\CG33892; Dmel\CG33894; Dmel\CG33896; Dmel\CG33898; Dmel\CG33900; Dmel\CG33902; Dmel\CG33904; Dmel\CG33906; Dmel\CG33908; Dmel\CG33910; Dmel_CG17949; Dmel_CG33868; Dmel_CG33870; Dmel_CG33872; Dmel_CG33874; Dmel_CG33876; Dmel_CG33878; Dmel_CG33880; Dmel_CG33882; Dmel_CG33884; Dmel_CG33886; Dmel_CG33888; Dmel_CG33890; Dmel_CG33892; Dmel_CG33894; Dmel_CG33896; Dmel_CG33898; Dmel_CG33900; Dmel_CG33902; Dmel_CG33904; Dmel_CG33906; Dmel_CG33908; Dmel_CG33910; fj05g08; GL105; H2B; H2B 291A; H2B 291B; H2b 613; H2B clustered histone 1; H2B clustered histone 15; H2B clustered histone 17; H2B clustered histone 19; H2B clustered histone 2, pseudogene; H2B clustered histone 21; H2B clustered histone 5; H2B clustered histone 8; H2B GL105 antibody; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member M; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B histone family, member W, testis-specific; H2B I; H2B II; H2B III; H2B IV; H2B K; H2B type 12; H2B VI; H2B VII; H2B.1; H2B.1 antibody; H2B.1A; H2B.1B; H2B.2; H2B.U histone 1; H2B.W histone 1; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/o; H2B/q; H2B/r; H2B/S; H2B/t; H2B1; H2B1.1; H2B1.2; h2B-143; H2B2; H2b-221; H2b-291b; H2b-613; H2Bb; H2BC1; H2BC10; H2BC15; H2BC17; H2BC19; H2BC21; H2BC2P; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2b-f; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFO; H2BFQ; h2bfr; H2BFS; H2BFT; H2BFU; H2BFWT; H2BGL105; H2B-I; H2B-II; H2B-III; H2B-IV; H2BJ; H2b-j; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2b-l; H2b-n; H2BQ; H2BS14; H2BS14p; H2BU1; H2B-VI; H2B-VII; H2BW1; HIRA-interacting protein 1; HIRA-interacting protein 2; HIRIP1; HIRIP2; His2B; His2B:CG17949; His2B:CG17949-PA; His2B:CG33868; His2B:CG33868-PA; His2B:CG33870; His2B:CG33870-PA; His2B:CG33872; His2B:CG33872-PA; His2B:CG33874; His2B:CG33874-PA; His2B:CG33876; His2B:CG33876-PA; His2B:CG33878; His2B:CG33878-PA; His2B:CG33880; His2B:CG33880-PA; His2B:CG33882; His2B:CG33882-PA; His2B:CG33884; His2B:CG33884-PA; His2B:CG33886; His2B:CG33886-PA; His2B:CG33888; His2B:CG33888-PA; His2B:CG33890; His2B:CG33890-PA; His2B:CG33892; His2B:CG33892-PA; His2B:CG33894; His2B:CG33894-PA; His2B:CG33896; His2B:CG33896-PA; His2B:CG33898; His2B:CG33898-PA; His2B:CG33900; His2B:CG33900-PA; His2B:CG33902; His2B:CG33902-PA; His2B:CG33904; His2B:CG33904-PA; His2B:CG33906; His2B:CG33906-PA; His2B:CG33908; His2B:CG33908-PA; His2B:CG33910; His2B:CG33910-PA; HIST1H2B7; HIST1H2B7L3; hist1h2ba; HIST1H2BB; HIST1H2BB antibody; Hist1h2bc; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; Hist1h2bh; HIST1H2BI; Hist1h2bj; hist1h2bj.L; hist1h2bj.S; HIST1H2BK; HIST1H2BL
Gene Symbols H2B, H2bc1, H2BC10, H2BC11, H2BC12, H2BC13, H2BC14, H2BC15, H2BC17, H2bc18, H2BC21, H2BC3, H2BC4, H2BC5, H2BC8, H2BC9, H2BE1, H2BU1, H2BW1, H2BW2, HIST1H2BA, HIST1H2BD, HIST1H2BJ, HIST1H2BM, HIST1H2BO, LOC102724334
Host Species Rabbit
Immunogen Histone H2B synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminus of human histone H2B. This sequence is well conserved in rat, mouse, fish, and drosophila histone H2B, and has low homology to other histone family members.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 102724334, 114483833, 128312, 158983, 24829, 255626, 286436, 291157, 3017, 3018, 319177, 319178, 319181, 319182, 319183, 319184, 319186, 319190, 361247, 440689, 68024, 680312, 691488, 8339, 8340, 8341, 8342, 8345, 8346, 8347, 8348, 8349, 85236, 8970
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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