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Invitrogen™ H3.3 G34R oncohistone mutant Recombinant Rabbit Monoclonal Antibody (4H1L8)

Catalog No. 703360
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70-336-0 100 μg
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Catalog No. 70-336-0 Supplier Invitrogen™ Supplier No. 703360
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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Frog. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen H3.3 G34R oncohistone mutant
Applications Western Blot
Classification Recombinant Monoclonal
Clone 4H1L8
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene H3-3A
Gene Accession No. P84243
Gene Alias H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3.3; H3.3 G34R; H3.3A; H3.3B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3B; H3FT; H3t; Histone 3.3; Histone cluster 3; Histone H3; Histone H3.3; Histone H3.3 G34R; Histone H3.3G34R; PP781
Gene Symbols H3-3A, H3-3B
Host Species Rabbit
Immunogen Peptides corresponding to human Histone H3.3 G34R/V [1)aa7-aa15 2)aa7-aa15].
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3020, 3021
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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