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Histone H3.3 Mouse anti-Human, Active Motif™
SDP

Catalog No. 501993857
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50-199-3857 100 μg
50-199-3858 10 μg
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Catalog No. 50-199-3857 Supplier Active Motif Supplier No. 91191
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Description

Mouse Recombinant Monoclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Specifications

Antigen Histone H3.3
Applications ChIP sequencing (ChIP-seq), Western Blot
Classification Monoclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene H3-3A
Gene Accession No. P84243
Gene Alias BOS_15646; CG5825; CG5825 gene product from transcript CG5825-RA; CG5825-PA; CG5825-PC; CG5825-PD; CG8989; dH3.3A; Dmel\CG5825; Dmel_CG5825; H3 histone, family 3A; H3.3; H3.3A; H3.3B; H3.4; H3.A; H3.B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3B; H3FT; H3L-like histone; H3t; His3.3; His3.3A; His-3.3A; His3.3A-PA; His3.3A-PC; His3.3A-PD; His3.3B; Histone cluster 3; Histone H3; Histone H3.3; histone H3.3 variant; Histone H3.3A; Histone H3.3B; histone H3.3-like; histone variant 3.3; histone variant H3.3; LOC100054462; MGC126886; MGC126888; PH3; PP781
Gene Symbols H3-3A
Host Species Mouse
Immunogen This antibody was raised against a peptide corresponding to amino acids 21-39 of human Histone H3.3.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3020
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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