Histone H3.3 Mouse anti-Human, Active Motif™

Mouse Recombinant Monoclonal Antibody

Supplier:  Active Motif 91192

Catalog No. 50-199-3858

Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Specifications

• Antigen: Histone H3.3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: H3-3A
• Gene Alias: BOS_15646; CG5825; CG5825 gene product from transcript CG5825-RA; CG5825-PA; CG5825-PC; CG5825-PD; CG8989; dH3.3A; Dmel\CG5825; Dmel_CG5825; H3 histone, family 3A; H3.3; H3.3A; H3.3B; H3.4; H3.A; H3.B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3B; H3FT; H3L-like histone; H3t; His3.3; His3.3A; His-3.3A; His3.3A-PA; His3.3A-PC; His3.3A-PD; His3.3B; Histone cluster 3; Histone H3; Histone H3.3; histone H3.3 variant; Histone H3.3A; Histone H3.3B; histone H3.3-like; histone variant 3.3; histone variant H3.3; LOC100054462; MGC126886; MGC126888; PH3; PP781
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 3020
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ChIP sequencing (ChIP-seq), Western Blot
• Concentration: 1 mg/mL
• Formulation: 140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
• Gene Accession No.: P84243
• Gene Symbols: H3-3A
• Immunogen: This antibody was raised against a peptide corresponding to amino acids 21-39 of human Histone H3.3.
• Quantity: 10 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a