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Histone H3.3K27M Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501993700
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50-199-3700 10 μL
50-199-3699 100 μL
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Catalog No. 50-199-3700 Supplier Active Motif Supplier No. 61804
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Description

Rabbit Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Specifications

Antigen Histone H3.3K27M
Applications Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene H3-3A
Gene Accession No. P84243
Gene Alias BOS_15646; CG5825; CG5825 gene product from transcript CG5825-RA; CG5825-PA; CG5825-PC; CG5825-PD; CG8989; dH3.3A; Dmel\CG5825; Dmel_CG5825; H3 histone, family 3A; H3.3; H3.3A; H3.3B; H3.4; H3.A; H3.B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3B; H3FT; H3L-like histone; H3t; His3.3; His3.3A; His-3.3A; His3.3A-PA; His3.3A-PC; His3.3A-PD; His3.3B; Histone cluster 3; Histone H3; Histone H3.3; histone H3.3 variant; Histone H3.3A; Histone H3.3B; histone H3.3-like; histone variant 3.3; histone variant H3.3; LOC100054462; MGC126886; MGC126888; PH3; PP781
Gene Symbols H3-3A
Host Species Rabbit
Immunogen This antibody was generated using a peptide containing a methionine substitution at lysine 27 of human Histone H3.
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3020
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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