Histone H3 ( (K4) Rabbit, Clone: RM186, Abnova™
Rabbit monoclonal antibody raised against synthetic peptide of human Histone H3 (K4).
Manufacturer: Abnova Corporation MAB12789
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq]
|Histone H3 ( (K4)|
|Rabbit monoclonal antibody raised against synthetic peptide of human Histone H3 (K4).|
|In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)|
|Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|This antibody recognizes Histone H3 that is unmodified at Lys 4 but does not recognize acetylated or methylated Lys 4. The antibody binding specificity allows for modifications of Arg 2, Thr 3, and/or other modifications in Histone H3.|
|ELISA, Western Blot|
|ELISA (0.5 ug/mL-1 ug/mL) Western Blot (1 ug/mL-2 ug/mL) The optimal working dilution should be determined by the end user.|
|A synthetic peptide corresponding to residues surrounding K4 at N-terminus region of Histone H3.|
|Protein A purification|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok