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Histone H3K122me1 Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501992700
Encompass
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10 μL
200 μL
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Catalog No. Quantity
50-199-2700 10 μL
50-199-2699 200 μL
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Catalog No. 50-199-2700 Supplier Active Motif Supplier No. 39368
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Description

Rabbit Polyclonal Antibody

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

Antigen Histone H3K122me1
Applications Dot Blot, Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Host Species Rabbit
Immunogen This Histone H3 monomethyl Lys122 antibody was raised against a peptide containing monomethyl-lysine 122 of human histone H3.
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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