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  6. Histone H3K27me2me3 Monoclonal Antibody (7B11), Active Motif™ 

Histone H3K27me2me3 Monoclonal Antibody (7B11), Active Motif™
SDP

Catalog No. 501992711
Encompass
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100 μg
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Catalog No. Quantity
50-199-2711 10 μg
50-199-2712 100 μg
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Catalog No. 50-199-2711 Supplier Active Motif Supplier No. 39538
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Description

Mouse Monoclonal Antibody

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

Antigen Histone H3K27me2me3
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone 7B11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 10mM sodium phosphate with 150mM NaCl, 30% glycerol and 0.035% sodium azide; pH 7.5
Host Species Mouse
Immunogen This Histone H3 di/trimethyl Lys27 antibody was raised against a peptide including trimethyl-lysine 27 of histone H3.
Purification Method Protein A
Quantity 10 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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