Histone H3K4K9K18 (pan-biotinylated) Rabbit anti-Human, Biotin, Polyclonal, Active Motif™

Catalog No.	Quantity
50-199-4150	100 μL

Catalog No. 50-199-4150 Supplier Active Motif Supplier No. 61391

Description

Rabbit Polyclonal Antibody

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

• Antigen: Histone H3K4K9K18 (pan-biotinylated)
• Applications: Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Polyclonal
• Concentration: Conc. Not Determined
• Conjugate: Biotin
• Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
• Host Species: Rabbit
• Immunogen: This antibody was raised against a synthetic peptide containing biotin-Lys 4 of human Histone H3.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG