Histone H3R8me1 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Supplier:  Active Motif 39674

Catalog No. 50-199-4092

Description

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post tranlationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

• Antigen: Histone H3R8me1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H3-4
• Gene Alias: H3 histone family, member T; H3.4; H3/g; H3/t; H3FT; H3t; HIST3H3; histone 3, H3; histone cluster 3, H3; Histone H3.1t
• Host Species: Rabbit
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Dot Blot, Western Blot
• Concentration: Conc. Not Determined
• Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
• Gene Accession No.: Q16695
• Gene Symbols: H3-4
• Immunogen: This Histone H3 monomethyl Arg8 antibody was raised against a peptide containing monomethyl-Arg8 of human histone H3.
• Regulatory Status: RUO
• Gene ID (Entrez): 8290
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid