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Histone H3S10phS28ph Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501993915
Encompass
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10 μL
200 μL
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Catalog No. Quantity
50-199-3915 200 μL
50-199-3916 10 μL
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Catalog No. 50-199-3915 Supplier Active Motif Supplier No. 39147
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Description

Rabbit Polyclonal Antibody

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

Antigen Histone H3S10phS28ph
Applications ChIP Assay, Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with 30% glycerol and 0.035% sodium azide; pH
Host Species Rabbit
Immunogen This Histone H3 phospho Ser10,28 antibody was raised against a peptide including phosphorylated serine 28 of human Histone H3.
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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