Histone H3S28ph Rat anti-Human, Mouse, Rat, Clone: HTA28, Active Motif™

Catalog No.	Quantity
50-199-2631	100 μL

Catalog No. 50-199-2631 Supplier Active Motif Supplier No. 39098

Description

Rat Monoclonal Antibody

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specifications

• Antigen: Histone H3S28ph
• Applications: ELISA, Immunocytochemistry, Immunofluorescence
• Classification: Monoclonal
• Clone: HTA28
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.1M tris glycine with 150mM NaCl and 0.05% sodium azide; pH
• Gene: H3F3A
• Gene Accession No.: P84244
• Gene Symbols: H3F3A, H3F3B, H3F3C, HIST1H3B, Hist2h3c2
• Host Species: Rat
• Immunogen: This Histone H3 phospho Ser28 antibody was raised in rat against a peptide corresponding to amino acid residues 23-35 (phospho Ser 28) of human Histone H3.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 100360868, 15078, 15081, 289314, 310678, 314977
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2a