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Histone H4 (trimethyl K20) Rabbit, Clone: RM208, Abnova™

Catalog No. 89947518 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-947-518 100 μg
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Catalog No. 89-947-518 Supplier Abnova Corporation Supplier No. MAB12799
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Description

Rabbit monoclonal antibody raised against synthetic trimethyl peptide of human Histone H4 (trimethyl K20).

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. [provided by RefSeq]

Specifications

Antigen Histone H4 (trimethyl K20)
Applications ELISA, Western Blot
Classification Monoclonal
Clone RM208
Conjugate Unconjugated
Description Rabbit monoclonal antibody raised against synthetic trimethyl peptide of human Histone H4 (trimethyl K20).
Dilution ELISA (0.5 ug/mL-1 ug/mL) Western Blot (1 ug/mL-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Gene Alias H4/p/MGC24116
Gene Symbols HIST4H4
Host Species Rabbit
Immunogen A synthetic trimethyl peptide corresponding to residues surrounding K20 of Histone H4.
Purification Method Protein A purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 121504
Test Specificity This antibody reacts to Histone H4 trimethylated at Lysine 20. It may slightly cross react to dimethylated Lysine 20 at a higher concentration. No cross reactivity with non-modified Lysine 20, monomethylated Lysine 20, or other methylations in histone H4.
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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