Histone H4K20me1 Monoclonal Antibody (5E10-D8), Active Motif™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-2811	Active Motif 39728	10 μg
50-199-2810	Active Motif 39727	100 μg

Description

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Histone H4K20me1
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene Alias: BcDNA:RH52884; CELE_T10C6.11; CG31611; CG3379; CG3379 gene product from transcript CG3379-RA; CG3379-PA; CG3379-PB; CG3379-PC; CG3379-PD; CG33869; CG33871; CG33873; CG33875; CG33877; CG33879; CG33881; CG33883; CG33885; CG33887; CG33889; CG33891; CG33893; CG33895; CG33897; CG33899; CG33901; CG33903; CG33905; CG33907; CG33909; Dmel\CG3379; Dmel_CG3379; F07B7.11; F07B7.4; F45F2.12; FBtr0082962; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K20; H4.1; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4C1; H4c11; H4C12; H4C13; H4c14; H4C15; H4c2; H4C3; H4c4; H4C5; H4C6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K20; H4K20me; H4Lys20me; H4Lys20me1; H4M; H4r; his-20; his-22; His4; his-4; His4:CG31611; His4:CG33869; His4:CG33871; His4:CG33873;
• Gene Symbols: H4-16, H4C1, H4C14, H4C2, H4C5, H4C9
• Isotype: IgG1 κ
• Purification Method: Protein A
• Product Type: Antibody

• Clone: 5E10-D8
• Applications: ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Mouse
• Target Species: Human
• Gene Accession No.: P62805
• Gene ID (Entrez): 121504, 8294, 8359, 8366, 8367, 8370
• Immunogen: This Histone H4 monomethyl Lys20 was raised against a synthetic peptide containing monomethyl Lys20 of Histone H4.
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: H4C1