Histone H4K5ac/K8ac Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™

Catalog No.	Quantity
50-199-3818	100 μg
50-199-3819	10 μg

Catalog No. 50-199-3818 Supplier Active Motif Supplier No. 91319

Description

Mouse Recombinant Monoclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Histone H4K5ac/K8ac
• Applications: ChIP sequencing (ChIP-seq), Dot Blot, Western Blot
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
• Gene: HIST1H4B
• Gene Accession No.: P62804
• Gene Symbols: HIST1H4A, HIST1H4B, HIST2H4A
• Host Species: Mouse
• Immunogen: This antibody was raised against a full-length human H4 protein containing acetyl k5 and k8 (H4k5ack8ac).
• Purification Method: Protein A
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 502913, 64627, 679983
• Target Species: Human, Multi-species, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1