Invitrogen™ Histone Macro-H2A.1 Recombinant Rabbit Monoclonal Antibody (4D2O4)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA535752

Catalog No. PIMA535752

Description

Immunogen sequence: IHSEISNLAG FEVEAIINPT NADIDLKDDL GNTLEKKGGK EFVEAVLELR KKNGPLEVAG AAVSAGHGLP AKFVIHCNSP VWGADKCEEL LEKTVKNCLA L.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: Histone Macro-H2A.1
• Classification: Recombinant Monoclonal
• Concentration: 0.95 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O75367, Q02874, Q9QZQ8
• Gene Symbols: MACROH2A1
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human macroH2A1 (O75367).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 4D2O4
• Conjugate: Unconjugated
• Gene: MACROH2A1
• Gene Alias: Core histone macro-H2A.1; H2A histone family member Y; H2A histone family, member Y; H2A.y; H2A/y; H2AF12M; H2AFY; Histone H2A.y; histone macroH2A1; histone macroH2A1.1; histone macroH2A1.2; macroH2A1; MACROH2A1.1; macroH2A1.2; medulloblastoma antigen MU-MB-50.205; mH2A1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26914, 29384, 9555
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid