Invitrogen™ HIV1 gp120 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520488

Catalog No. PIPA520488

Description

PA5-20488 can be used with blocking peptide PEP-0608.

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

Specifications

• Antigen: HIV1 gp120
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: HIV Glycoprotein 120; HIV-1 Glycoprotein 120; Human immunodeficiency virus
• Immunogen: 16 amino acid peptide representing the major HIV-1 consensus sequence near the N-terminal region of V1/V2 loop.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: Maintain refrigerated at 2°C to 8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov