Invitrogen™ HIV1 gp120 Polyclonal Antibody, Biotin

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA173098

Catalog No. PA173098

Description

The PA1-73098 antibody reacts with HIV-1 gp120. PA1-73098 has been successfully used in Immunohistochemical, ELISA, Immunofluorescence and Western blot applications. The PA1-73098 antibody was raised against Purified native gp120 from strain IIIB.

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

Specifications

• Antigen: HIV1 gp120
• Classification: Polyclonal
• Conjugate: Biotin
• Gene Alias: HIV Glycoprotein 120; HIV-1 Glycoprotein 120; Human immunodeficiency virus
• Immunogen: Purified native gp120 from strain IIIB.
• Quantity: 1 mL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunohistochemistry, Western Blot
• Concentration: 5.0 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.2
• Host Species: Goat
• Purification Method: IgG fraction
• Regulatory Status: RUO
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG