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Invitrogen™ HIV1 gp120 Polyclonal Antibody, HRP
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Catalog No. PA173097
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PA173097 1 mL
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Catalog No. PA173097 Supplier Invitrogen™ Supplier No. PA173097
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Description

Goat Polyclonal Antibody

The PA1-73097 antibody reacts with HIV-1 gp120. PA1-73097 has been successfully used in ELISA, IHC, and IB applications. The PA1-73097 antibody was raised against Purified native gp120 from strain IIIB. NOTE: Sodium azide is a potent inhibitor of peroxidase!.

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HIV1 gp120
Applications ELISA, Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate HRP
Formulation PBS with 10mg/mL BSA and 0.002% thimerosal; pH 7.2
Gene Alias HIV Glycoprotein 120; HIV-1 Glycoprotein 120; Human immunodeficiency virus
Host Species Goat
Immunogen Purified native gp120 from strain IIIB.
Purification Method IgG fraction
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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