Invitrogen™ HJURP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552562

Catalog No. PIPA552562

Description

Immunogen sequence: TPVVQMATLT YETPQGLRIW GGRLIKERNE GEIQDSSMKP ADRTDGSVQA AAWGPELPSH RTVLGADSKS GEVDATSDQE ESVAWALAPA VPQSPLKNEL RRKYLTQVDI LLQGAEYFEC AGNRAGRDVR V Highest antigen sequence identity to the following orthologs: Mouse - 37%, Rat - 43%.

Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. It acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. It directly binds to Holliday junctions.

Specifications

• Antigen: HJURP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HJURP
• Gene Alias: 14-3-3-associated AKT substrate; 6430706D22Rik; A730008H23Rik; C330011F01Rik; FAKTS; fetal liver expressing gene 1; fetal liver expressing gene 1 protein homolog; Fetal liver-expressing gene 1 protein; FLEG1; Gm975; hFLEG1; Hjurp; Holliday junction recognition protein; mFleg1; RGD1305846; Up-regulated in lung cancer 9; URLC9
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55355
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8NCD3
• Gene Symbols: HJURP
• Immunogen: Recombinant protein corresponding to Human HJURP. Recombinant protein control fragment (Product #RP-89719).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov