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Invitrogen™ HJURP Polyclonal Antibody
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Catalog No. PIPA552562
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100 μL
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PIPA552562 100 μL
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Catalog No. PIPA552562 Supplier Invitrogen™ Supplier No. PA552562
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TPVVQMATLT YETPQGLRIW GGRLIKERNE GEIQDSSMKP ADRTDGSVQA AAWGPELPSH RTVLGADSKS GEVDATSDQE ESVAWALAPA VPQSPLKNEL RRKYLTQVDI LLQGAEYFEC AGNRAGRDVR V Highest antigen sequence identity to the following orthologs: Mouse - 37%, Rat - 43%.

Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. It acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. It directly binds to Holliday junctions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HJURP
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene HJURP
Gene Accession No. Q8NCD3
Gene Alias 14-3-3-associated AKT substrate; 6430706D22Rik; A730008H23Rik; C330011F01Rik; FAKTS; fetal liver expressing gene 1; fetal liver expressing gene 1 protein homolog; Fetal liver-expressing gene 1 protein; FLEG1; Gm975; hFLEG1; Hjurp; Holliday junction recognition protein; mFleg1; RGD1305846; Up-regulated in lung cancer 9; URLC9
Gene Symbols HJURP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human HJURP. Recombinant protein control fragment (Product #RP-89719).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55355
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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