Invitrogen™ HJURP Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116931

Catalog No. PIPA5116931

Description

Positive Samples: Mouse testis, Mouse brain, Mouse spleen, Rat testis, Rat thymus Immunogen sequence: MLGTLRAMEG EDVEDDQLLQ KLRASRRRFQ RRMQRLIEKY NQPFEDTPVV QMATLTYETP QGLRIWGGRL IKERNEGEIQ DSSMKPADRT DGSVQAAAWG PELPSHRTVL GADSKSGEVD ATSDQEESVA WALAPAVPQS PLKNELRRKY LTQVDILLQG AEYFECAGNR AGRDVRVTPL PSLASPAVPA.

Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. It acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. It directly binds to Holliday junctions.

Specifications

• Antigen: HJURP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: HJURP
• Gene Alias: 14-3-3-associated AKT substrate; 6430706D22Rik; A730008H23Rik; C330011F01Rik; FAKTS; fetal liver expressing gene 1; fetal liver expressing gene 1 protein homolog; Fetal liver-expressing gene 1 protein; FLEG1; Gm975; hFLEG1; Hjurp; Holliday junction recognition protein; mFleg1; RGD1305846; Up-regulated in lung cancer 9; URLC9
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 316602, 381280
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.02 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q6PG16
• Gene Symbols: HJURP
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human HJURP (NP_0608803).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG