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Invitrogen™ HJURP Polyclonal Antibody
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Catalog No. PIPA5116931
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100 μL
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PIPA5116931 100 μL
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Catalog No. PIPA5116931 Supplier Invitrogen™ Supplier No. PA5116931
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse testis, Mouse brain, Mouse spleen, Rat testis, Rat thymus Immunogen sequence: MLGTLRAMEG EDVEDDQLLQ KLRASRRRFQ RRMQRLIEKY NQPFEDTPVV QMATLTYETP QGLRIWGGRL IKERNEGEIQ DSSMKPADRT DGSVQAAAWG PELPSHRTVL GADSKSGEVD ATSDQEESVA WALAPAVPQS PLKNELRRKY LTQVDILLQG AEYFECAGNR AGRDVRVTPL PSLASPAVPA.

Holliday junction recognition protein (HJURP) is a centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. It acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. It directly binds to Holliday junctions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HJURP
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.02 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene HJURP
Gene Accession No. Q6PG16
Gene Alias 14-3-3-associated AKT substrate; 6430706D22Rik; A730008H23Rik; C330011F01Rik; FAKTS; fetal liver expressing gene 1; fetal liver expressing gene 1 protein homolog; Fetal liver-expressing gene 1 protein; FLEG1; Gm975; hFLEG1; Hjurp; Holliday junction recognition protein; mFleg1; RGD1305846; Up-regulated in lung cancer 9; URLC9
Gene Symbols HJURP
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human HJURP (NP_0608803).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 316602, 381280
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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