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Invitrogen™ HK2 Monoclonal Antibody (3D3)
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Catalog No. PIMA515679
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100 μL
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Catalog No. Quantity
PIMA515679 100 μL
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Catalog No. PIMA515679 Supplier Invitrogen™ Supplier No. MA515679
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Description

Mouse Monoclonal Antibody

MA5-15679 targets HK2 in indirect ELISA, FACS, IHC and WB applications and shows reactivity with Human samples. The MA5-15679 immunogen is purified recombinant fragment of human HK2 expressed in E. Coli. MA5-15679 detects HK2 which has a predicted molecular weight of approximately 102kDa.

In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HK2
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 3D3
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene Hk2
Gene Accession No. P52789
Gene Alias AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738
Gene Symbols Hk2
Host Species Mouse
Immunogen Purified recombinant fragment of human HK2 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3099
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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