Invitrogen™ HK2 Monoclonal Antibody (7E7)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA532952

Catalog No. PIMA532952

Description

Purity is > 95% by SDS-PAGE.

In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.

Specifications

• Antigen: HK2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P27881, P52789
• Gene Symbols: Hk2
• Immunogen: Synthetic peptide, corresponding to amino acids N-terminus of Human Hexokinase-2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Western Blot
• Clone: 7E7
• Conjugate: Unconjugated
• Gene: Hk2
• Gene Alias: AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738
• Host Species: Mouse
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25059, 3099
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid