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HK2 Monoclonal Antibody (H.738.7), Invitrogen™

Catalog No. PIMA514849
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100 μL
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Catalog No. Quantity
PIMA514849 100 μL
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Catalog No. PIMA514849 Supplier Thermo Scientific Supplier No. MA514849

Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HK2
Applications Western Blot
Classification Monoclonal
Clone H.738.7
Concentration 24 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Hk2
Gene Accession No. O08528, P27881, P52789
Gene Alias AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738
Gene Symbols Hk2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to the sequence of human
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15277, 25059, 3099
Target Species Human, Mouse, Non-human Primate, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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