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Invitrogen™ HK2 Polyclonal Antibody
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Catalog No. PIPA583021
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100 μL
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PIPA583021 100 μL
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Catalog No. PIPA583021 Supplier Invitrogen™ Supplier No. PA583021
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GKLSPELLNT GRFETKDISD IEGEKDGIRK AREVLMRLGL DPTQEDCVAT HRICQIVSTR SA Highest antigen sequence indentity to the following orthologs: Mouse - 81%, Rat - 82%.

In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen HK2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Hk2
Gene Accession No. P52789
Gene Alias AI642394; DKFZp686M1669; Hexokinase; hexokinase 2; hexokinase II; hexokinase type II; Hexokinase-2; hexokinase-2 muscle; hexokinase-2, muscle; Hexokinase-B; HK II; Hk2; HKII; HXK2; muscle form hexokinase; OTTHUMP00000202738
Gene Symbols Hk2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human HK2. Recombinant protein control fragment (Product #RP-95130).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3099
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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